Jens D. Mikkelsen
Professor
Management and administration
Blegdamsvej 3
2200 København N.
- Published
Low back pain scores correlate with the cytokine mRNA level in lumbar disc biopsies: a study of inflammatory markers in patients undergoing lumbar spinal fusion
Aripaka, S. S., jmn329, jmn329, Jørgensen, Louise Møller, Chughtai, S. A., Gaarde, C., Bendix, T. & Mikkelsen, Jens D., 2021, In: European Spine Journal. 30, p. 2967–2974 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lynx1 and Aβ1-42 bind competitively to multiple nicotinic acetylcholine receptor subtypes
Thomsen, M. S., Arvaniti, M., Jensen, M. M., Shulepko, M. A., Dolgikh, D. A., Pinborg, Lars Hageman, Härtig, W., Lyukmanova, E. N. & Mikkelsen, Jens D., Oct 2016, In: Neurobiology of Aging. 46, p. 13-21 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Melatonin controls seasonal breeding by a network of hypothalamic targets
Revel, F. G., Masson-Pévet, M., Pévet, P., Mikkelsen, Jens D. & Simonneaux, V., 2009, In: Neuroendocrinology. 90, 1, p. 1-14 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabotropic glutamate receptor 2 and corticotrophin-releasing factor receptor-1 gene expression is differently regulated by BDNF in rat primary cortical neurons
Jørgensen, C. V., Klein, A. B., El-Sayed, M., Knudsen, G. M. & Mikkelsen, Jens D., 2013, In: Synapse. 67, 11, p. 794-800Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microduplication of 15q13.3 and Xq21.31 in a family with tourette syndrome and comorbidities
Melchior, L., Bertelsen, B., Debes, Nanette M Monique Mol, Groth, C., Skov, L., Mikkelsen, Jens D., Brøndum-Nielsen, K. & Tümer, Asuman Zeynep, 2013, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 162, 8, p. 825-831 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation of anxiety circuits by serotonergic systems
Lowry, C. A., Johnson, P. L., Hay-Schmidt, Anders, Mikkelsen, Jens D. & Shekhar, A., Dec 2005, In: Stress: The International Journal on the Biology of Stress . 8, 4, p. 233-246 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
N1H- and N1-Substituted Phenylguanidines as alpha 7 Nicotinic Acetylcholine (nACh) Receptor Antagonists: Structure-Activity Relationship Studies
Alwassil, O., Khatri, S., Schulte, M. K., Aripaka, S. S., Mikkelsen, Jens D. & Dukat, M., 2021, In: ACS Chemical Neuroscience. 12, 12, p. 2194-2201 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuropeptide Y (NPY) and NPY receptors in the rat pineal gland
Mikkelsen, Jens D., Hauser, Frank & Olcese, J., 1999, In: Advances in Experimental Medicine and Biology. 460, p. 95-107 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Ovariectomy Drives Asynchronous Changes in Serotonin Receptor 2A and Transporter Availability in Rats
Frimer, N. A., Overgaard, A., Lie, M. E. K., Mikkelsen, Jens D. & Frokjaer, V. G., 2015, In: Journal of Steroids & Hormonal Science. 6, 3, p. 1-5 5 p., 1000161.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perinatal nicotine treatment induces transient increases in NACHO protein levels in the rat frontal cortex
Wichern, F., Jensen, M. M., Christensen, D. Z., Mikkelsen, Jens D., Gondré-Lewis, M. C. & Thomsen, M. S., 27 Mar 2017, In: Neuroscience. 346, p. 278-283 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Photoperiodic Co-Regulation of Kisspeptin, Neurokinin B and Dynorphin in the Hypothalamus of a Seasonal Rodent
Bartzen-Sprauer, J., Klosen, P., Ciofi, P., Mikkelsen, Jens D. & Simonneaux, V., Aug 2014, In: Journal of Neuroendocrinology. 26, 8, p. 510-520 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plaque deposition dependent decrease in 5-HT2A serotonin receptor in AbetaPPswe/PS1dE9 amyloid overexpressing mice
Holm, P., Ettrup, A., Klein, A. B., Santini, M. A., El-Sayed, M., Elvang, A. B., Stensbøl, T. B., Mikkelsen, Jens D., Knudsen, Gitte Moos & Kleijn, S. A., 1 Jan 2010, In: Journal of Alzheimer's Disease. 20, 4, p. 1201-13 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Positive allosteric modulators of the α7 nicotinic acetylcholine receptor potentiate glutamate release in the prefrontal cortex of freely-moving rats
Bortz, D. M., Upton, B. A., Mikkelsen, Jens D. & Bruno, J. P., Dec 2016, In: Neuropharmacology. 111, p. 78-91Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease
Jensen, M. M., Mikkelsen, Jens D., Arvaniti, M., Pinborg, Lars Hageman & Thomsen, M. S., 1 Apr 2015, In: Neurobiology of Aging. 36, 4, p. 1629-1638 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of the functional expression of the Ca2+‐activated K+ channel KCa3.1 on microglia from adult human neocortical tissue
Blomster, L. V., Strøbaek, D., Hougaard, Charlotte Ørsted, Klein, J., Pinborg, Lars Hageman, Mikkelsen, Jens D. & Christophersen, P., Dec 2016, In: Glia. 64, 12, p. 2065-2078 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radiosynthesis and in vitro validation of (3)H-NS14492 as a novel high affinity alpha7 nicotinic receptor radioligand
Magnussen, J. H., Ettrup, A., Donat, C. K., Peters, D., Pedersen, M. H. F., Knudsen, G. M. & Mikkelsen, Jens D., 5 Sep 2015, In: European Journal of Pharmacology. 762, p. 35-41 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced basal and novelty-induced levels of activity-regulated cytoskeleton associated protein (Arc) and c-Fos mRNA in the cerebral cortex and hippocampus of APPswe/PS1ΔE9 transgenic mice
Christensen, D. Z., Thomsen, M. S. & Mikkelsen, Jens D., Jul 2013, In: Neurochemistry International. 63, 1, p. 54-60 7 p.Research output: Contribution to journal › Journal article › Research
- Published
Regional brain volumes, diffusivity, and metabolite changes after electroconvulsive therapy for severe depression
Jorgensen, A., Magnusson, P., Hanson, L. G., Kirkegaard, T., Benveniste, H., Lee, H., Svarer, C., Mikkelsen, Jens D., Fink-Jensen, Anders, Knudsen, G. M., Paulson, Olaf B., Bolwig, T. G. & Jørgensen, Martin Balslev, Feb 2016, In: Acta Psychiatrica Scandinavica. 133, 2, p. 154-164 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of brain-derived neurotrophic factor (BDNF) in the chronic unpredictable stress rat model and the effects of chronic antidepressant treatment
Larsen, M. H., Mikkelsen, Jens D., Hay-Schmidt, Anders & Sandi, C., 2010, In: Journal of Psychiatric Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reprogrammering af modne celler til neuroner
Mikkelsen, Jens D., Rasmussen, M. A., Meyer, M. & Knudsen, G. M., 2012, In: Ugeskrift for Laeger. 174, 12, p. 786Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response of substances co-expressed in hypothalamic magnocellular neurons to osmotic challenges in normal and Brattleboro rats
Bundzikova, J., Pirnik, Z., Zelena, D., Kiss, A. & Mikkelsen, Jens D., 2008, In: Cellular & Molecular Neurobiology. 28, 8, p. 1033-1047 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of Serotonin Transporter Changes in Depressive Responses to Sex-Steroid Hormone Manipulation: A Positron Emission Tomography Study
Frokjaer, V. G., Pinborg, Anja, Holst, K. K., Overgaard, A., Henningsson, S., Heede, M., Larsen, E. C., Jensen, P. S., Agn, M., Nielsen, A. P., Stenbæk, D. S., da Cunha-Bang, S., Lehel, S., Siebner, Hartwig Roman, Mikkelsen, Jens D., Svarer, C. & Knudsen, Gitte Moos, 15 Oct 2015, In: Biological Psychiatry. 78, 8, p. 534-43 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roles of RFRP-3 in the Daily and Seasonal Regulation of Reproductive Activity in Female Syrian Hamsters
Henningsen, J. B., Ancel, C., Mikkelsen, Jens D., Gauer, F. & Simonneaux, V., 1 Mar 2017, In: Endocrinology. 158, 3, p. 652-663 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roles of RFRP-3 in the daily and seasonal regulation of reproductive activity in female Syrian hamsters
Henningsen, J. B., Ancel, C., Mikkelsen, Jens D., Gauer, F. & Simonneaux, V., 2017, In: Endocrinology. 158, 3, p. 652-663Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective cognitive deficits and reduced hippocampal brain-derived neurotrophic factor mRNA expression in small-conductance calcium-activated K+ channel deficient mice
Jacobsen, J. P. R., Redrobe, J. P., Hansen, H. H., Petersen, S., Bond, C. T., Adelman, J. P., Mikkelsen, Jens D. & Mirza, N. R., 2009, In: Neuroscience. 163, 1, p. 73-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serotonergic stimulation of the rat hypothalamo-pituitary-adrenal axis: interaction between 5-HT1A and 5-HT2A receptors
Mikkelsen, Jens D., Hay-Schmidt, Anders & Kiss, A., Jun 2004, In: Annals of the New York Academy of Sciences. 1018, p. 65-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs
Abrams, J. K., Johnson, P. L., Hay-Schmidt, Anders, Mikkelsen, Jens D., Shekhar, A. & Lowry, C. A., 2005, In: Neuroscience. 133, 4, p. 983-97 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex differences in the photoperiodic regulation of RF-Amide related peptide (RFRP) and its receptor GPR147 in the syrian hamster
Henningsen, J. B., Poirel, V., Mikkelsen, Jens D., Tsutsui, K., Simonneaux, V. & Gauer, F., 15 Jun 2016, In: Journal of Comparative Neurology. 524, 9, p. 1825-1838 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatio-Temporal Alterations in Synaptic Density During Epileptogenesis in the Rat Brain
Mikkelsen, Jens D., trj450, trj450, Bascuñana, P., Bankstahl, M., Bankstahl, J. P. & Pazarlar, B. A., 2022, In: Neuroscience. 499, p. 142-151 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subacute effects of a single dose of psilocybin on biomarkers of inflammation in healthy humans: An open-label preliminary investigation
Burmester, D. R., Madsen, M. K., Szabo, A., trj450, trj450, Stenbæk, Dea Siggaard, Frøkjær, Vibe Gedsø, Elfving, B., Mikkelsen, Jens D., Knudsen, Gitte Moos & Fisher, Patrick Mac Donald, 2023, In: Comprehensive Psychoneuroendocrinology. 13, 7 p., 100163.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synaptic Density and Neuronal Metabolic Function Measured by Positron Emission Tomography in the Unilateral 6-OHDA Rat Model of Parkinson’s Disease
Raval, N. R., Gudmundsen, F., Juhl, M., Andersen, Ida Vang, Speth, N., Videbæk, A., Petersen, I. N., Mikkelsen, Jens D., Fisher, P. M. D., Herth, Matthias Manfred, Plavén-Sigray, P., Knudsen, Gitte Moos & Palner, M., 2021, In: Frontiers in Synaptic Neuroscience. 13, 13 p., 715811.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synaptic vesicle glycoprotein 2A (SV2A) levels in the cerebral cortex in patients with Alzheimer's disease: a radioligand binding study in postmortem brains
Mikkelsen, Jens D., Kaad, S., trj450, trj450 & Finsen, Bente, 2023, In: Neurobiology of Aging. 129, p. 50-57 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synergistic effect of serotonin 1A and serotonin 1B/D receptor agonists in the treatment of L-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned rats
Thomsen, M., Stoica, A., Christensen, K. V., Fryland, T., Mikkelsen, Jens D. & Hansen, J. B., 2022, In: Experimental Neurology. 358, 12 p., 114209.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systemic treatment with a selective TNFR2 agonist alters the central and peripheral immune responses and transiently improves functional outcome after experimental ischemic stroke
Thougaard, E., Nielsen, P. V., Forsberg, A., Phuong, V., Velasco, A. M., Wlodarczyk, A., Wajant, H., Lang, I., Mikkelsen, Jens D., Clausen, B. H., Brambilla, R. & Lambertsen, K. L., 2023, In: Journal of Neuroimmunology. 385, 17 p., 578246.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TSPO Imaging in Glioblastoma Multiforme: A Direct Comparison Between 123I-CLINDE SPECT, 18F-FET PET, and Gadolinium-Enhanced MR Imaging
Jensen, P., Feng, L., Law, Ian, Svarer, C., Knudsen, G. M., Mikkelsen, Jens D., de Nijs, R., Larsen, V. A., Dyssegaard, A., Thomsen, G., Fischer, W., Guilloteau, D. & Pinborg, Lars Hageman, Sep 2015, In: Journal of Nuclear Medicine. 56, 9, p. 1386-90 5 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Targeting Dopamine D3 and Serotonin 5-HT1A and 5-HT2A Receptors for Developing Effective Antipsychotics: Synthesis, Biological Characterization, and Behavioral Studies
Brindisi, M., Butini, S., Franceschini, S., Brogi, S., Trotta, F., Ros, S., Cagnotto, A., Salmona, M., Casagni, A., Andreassi, M., Saponara, S., Gorelli, B., Weikop, P., Mikkelsen, Jens D., Scheel-Kruger, J., Sandager-Nielsen, K., Novellino, E., Campiani, G. & Gemma, S., 26 Nov 2014, In: Journal of Medicinal Chemistry. 57, 22, p. 9578-9597 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Temporal and spatial changes in synaptic vesicle glycoprotein 2A (SV2A) under kainic acid induced epileptogenesis: An autoradiographic study
Pazarlar, B. A., Madsen, C. A., Oyar, E. Ö., Eğilmez, C. B. & Mikkelsen, Jens D., 2022, In: Epilepsy Research. 183, 10 p., 106926.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tesofensine induces appetite suppression and weight loss with reversal of low forebrain dopamine levels in the diet-induced obese rat
Hansen, H. H., Jensen, M. M., Overgaard, A., Weikop, Pia & Mikkelsen, Jens D., 2013, In: Pharmacology, Biochemistry and Behavior. 110, p. 265-271 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Cholinergic but not the Serotonergic Phenotype of Anew Neuronal Cell Line is Sensitive to β-Amyloid-Induced Toxicity
Olesen, O. F., Fjord-Larsen, L. & Mikkelsen, Jens D., 1998, Progress in Alzheimer’s and Parkinson’s Diseases . p. 495-501 7 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The Preoptic Area and the RFamide-Related Peptide Neuronal System Gate Seasonal Changes in Chemosensory Processing
Jennings, K. J., Chasles, M., Cho, H., Mikkelsen, Jens D., Bentley, G., Keller, M. & Kriegsfeld, L. J., Nov 2017, In: Integrative and Comparative Biology. 57, 5, p. 1055-1065 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The alpha7 nicotinic receptor agonist SSR180711 increases activity regulated cytoskeleton protein (Arc) gene expression in the prefrontal cortex of the rat
Kristensen, S., Thomsen, M. S., Hansen, H. H., Timmermann, D. B., Hay-Schmidt, Anders & Mikkelsen, Jens D., 17 May 2007, In: Neuroscience Letters. 418, 2, p. 154-8 5 p.Research output: Contribution to journal › Journal article › Research
- Published
The effect of perinatal exposure to ethinyl oestradiol or a mixture of endocrine disrupting pesticides on kisspeptin neurons in the rat hypothalamus
Overgaard, A., Holst, K., Mandrup, K., Boberg, J., Christiansen, S., Jacobsen, A. P., Hass, U. & Mikkelsen, Jens D., 2013, In: NeuroToxicology. 37, p. 154-162 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The mGlu2/3 Receptor Agonists LY354740 and LY379268 Differentially Regulate Restraint-Stress-Induced Expression of c-Fos in Rat Cerebral Cortex
Menezes, M. M., Santini, M., Benvega, M. J., Marek, G. J., Merchant, K. M., Mikkelsen, Jens D. & Svensson, K. A., 2013, In: Neuroscience Journal. 2013, 8 p., 736439.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The neuroanatomy of the kisspeptin system in the mammalian brain
Mikkelsen, Jens D. & Simonneaux, V., 2008, In: Peptides. 30, 1, p. 26-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The nicotinic alpha7 acetylcholine receptor agonist ssr180711 is unable to activate limbic neurons in mice overexpressing human amyloid-beta1-42
Søderman, A., Thomsen, M. S., Hansen, H. H., Nielsen, E. Ø., Jensen, M. S., West, M. J. & Mikkelsen, Jens D., 28 Aug 2008, In: Brain Research. 1227, p. 240-7 8 p.Research output: Contribution to journal › Journal article › Research
- Published
The pan-Kv7 (KCNQ) Channel Opener Retigabine Inhibits Striatal Excitability by Direct Action on Striatal Neurons In Vivo
Hansen, H. H., Weikop, P., Mikkelsen, M. D., Rode, F. & Mikkelsen, Jens D., Jan 2017, In: Basic & Clinical Pharmacology & Toxicology Online. 120, 1, p. 46-51 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The selective alpha7 nicotinic acetylcholine receptor agonist A-582941 activates immediate early genes in limbic regions of the forebrain: Differential effects in the juvenile and adult rat
Thomsen, M. S., Mikkelsen, Jens D., Timmermann, D. B., Peters, D. A., Hay-Schmidt, Anders, Martens, H. A., Hansen, H. H. & Thomsen, M. S., 23 Jun 2008, In: Neuroscience. 154, 2, p. 741-53 13 p.Research output: Contribution to journal › Journal article › Research
- Published
The variability of translocator protein signal in brain and blood of genotyped healthy humans using in vivo 123I-CLINDE SPECT imaging: A test-retest study
Feng, L., Jensen, P., Thomsen, G., Dyssegaard, A., Svarer, C., Knudsen, L. V., Møller, Kirsten, Thomsen, C., Mikkelsen, Jens D., Guilloteau, D., Knudsen, Gitte Moos & Pinborg, Lars Hageman, 2017, In: Journal of Nuclear Medicine. 58, 6, p. 989-995 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The α7 nicotinic acetylcholine receptor complex: one, two or multiple drug targets?
Thomsen, M. S. & Mikkelsen, Jens D., May 2012, In: Current Drug Targets. 13, 5, p. 707-20 14 p.Research output: Contribution to journal › Journal article › Research
- Published
The α7 nicotinic acetylcholine receptor ligands methyllycaconitine, NS6740 and GTS-21 reduce lipopolysaccharide-induced TNF-α release from microglia
Thomsen, M. S. & Mikkelsen, Jens D., 15 Oct 2012, In: Journal of Neuroimmunology. 251, 1-2, p. 65-72 8 p.Research output: Contribution to journal › Journal article › Research
ID: 32177473
Most downloads
-
633
downloads
Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
278
downloads
Functional interaction between Lypd6 and nicotinic acetylcholine receptors
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
243
downloads
Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons
Research output: Contribution to journal › Journal article › Research › peer-review
Published