Jens D. Mikkelsen
Professor
Management and administration
Blegdamsvej 3
2200 København N.
- 1988
- Published
Immunohistochemical localisation and developmental aspects of epidermal growth factor in the rat
Raaberg, L., Nexo, E., Mikkelsen, Jens D. & Poulsen, Steen Seier, 1 Jul 1988, In: Histochemistry. 89, 4, p. 351-356 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1991
- Published
Induction, purification and characterization of chitinase isolated from pea leaves inoculated with Ascochyta pisi
Vad, K., Mikkelsen, Jens D. & Collinge, David B., 1 Apr 1991, In: Planta. 184, 1, p. 24-29 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
- Published
Efferent connections from the lateral hypothalamic region and the lateral preoptic area to the hypothalamic paraventricular nucleus of the rat
Larsen, P. J., Hay-Schmidt, Anders & Mikkelsen, Jens D., 1994, In: Journal of Comparative Neurology. 342, 2, p. 299-319 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induced resistance in sugar beet against Cercospora beticola: Induction by dichloroisonicotinic acid is independent of chitinase and β-1,3-glucanase transcript accumulation
Nielsen, K. K., Bojsen, K., Collinge, David B. & Mikkelsen, Jens D., 1 Jan 1994, In: Physiological and Molecular Plant Pathology. 45, 2, p. 89-99 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
Isoform-specific binding of human apolipoprotein E to the non-amyloid β component of Alzheimer's disease amyloid
Olesen, O. F., Mikkelsen, Jens D., Gerdes, C. & Jensen, P. H., Feb 1997, In: Molecular Brain Research. 44, 1, p. 105-112 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Aβ Induces Cell Death in Pc12 Cells and Tau-Transfected Cho Cells, but only Tau Phosphorylation in Pc12 Cells
Fjord-Larsen, L., Mikkelsen, Jens D. & Olesen, O. F., 1998, Progress in Alzheimer’s and Parkinson’s Diseases . p. 257-263 7 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The Cholinergic but not the Serotonergic Phenotype of Anew Neuronal Cell Line is Sensitive to β-Amyloid-Induced Toxicity
Olesen, O. F., Fjord-Larsen, L. & Mikkelsen, Jens D., 1998, Progress in Alzheimer’s and Parkinson’s Diseases . p. 495-501 7 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Amyloid β neurotoxicity in the cholinergic but not in the serotonergic phenotype of RN46A cells
Olesen, O. F., Dagø, L. & Mikkelsen, Jens D., 15 Jun 1998, In: Molecular Brain Research. 57, 2, p. 266-274 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Neuropeptide Y (NPY) and NPY receptors in the rat pineal gland
Mikkelsen, Jens D., Hauser, Frank & Olcese, J., 1999, In: Advances in Experimental Medicine and Biology. 460, p. 95-107 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Developmental expression of α-synuclein in rat hippocampus and cerebral cortex
Petersen, K., Olesen, O. F. & Mikkelsen, Jens D., Jun 1999, In: Neuroscience. 91, 2, p. 651-659 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
Hypocretin (orexin) in the rat pineal gland: A central transmitter with effects on noradrenaline-induced release of melatonin
Mikkelsen, Jens D., Hauser, Frank, DeLecea, L., Sutcliffe, J. G., Kilduff, T. S., Calgari, C., Pévet, P. & Simonneaux, V., 2001, In: European Journal of Neuroscience. 14, 3, p. 419-425 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Serotonergic stimulation of the rat hypothalamo-pituitary-adrenal axis: interaction between 5-HT1A and 5-HT2A receptors
Mikkelsen, Jens D., Hay-Schmidt, Anders & Kiss, A., Jun 2004, In: Annals of the New York Academy of Sciences. 1018, p. 65-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs
Abrams, J. K., Johnson, P. L., Hay-Schmidt, Anders, Mikkelsen, Jens D., Shekhar, A. & Lowry, C. A., 2005, In: Neuroscience. 133, 4, p. 983-97 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation of anxiety circuits by serotonergic systems
Lowry, C. A., Johnson, P. L., Hay-Schmidt, Anders, Mikkelsen, Jens D. & Shekhar, A., Dec 2005, In: Stress: The International Journal on the Biology of Stress . 8, 4, p. 233-246 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
The alpha7 nicotinic receptor agonist SSR180711 increases activity regulated cytoskeleton protein (Arc) gene expression in the prefrontal cortex of the rat
Kristensen, S., Thomsen, M. S., Hansen, H. H., Timmermann, D. B., Hay-Schmidt, Anders & Mikkelsen, Jens D., 17 May 2007, In: Neuroscience Letters. 418, 2, p. 154-8 5 p.Research output: Contribution to journal › Journal article › Research
- 2008
- Published
Kisspeptin and the seasonal control of reproduction in hamsters
Simonneaux, V., Ansel, L., Revel, F. G., Klosen, P., Pévet, P. & Mikkelsen, Jens D., 2008, In: Peptides. 30, 1, p. 146-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response of substances co-expressed in hypothalamic magnocellular neurons to osmotic challenges in normal and Brattleboro rats
Bundzikova, J., Pirnik, Z., Zelena, D., Kiss, A. & Mikkelsen, Jens D., 2008, In: Cellular & Molecular Neurobiology. 28, 8, p. 1033-1047 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The neuroanatomy of the kisspeptin system in the mammalian brain
Mikkelsen, Jens D. & Simonneaux, V., 2008, In: Peptides. 30, 1, p. 26-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The selective alpha7 nicotinic acetylcholine receptor agonist A-582941 activates immediate early genes in limbic regions of the forebrain: Differential effects in the juvenile and adult rat
Thomsen, M. S., Mikkelsen, Jens D., Timmermann, D. B., Peters, D. A., Hay-Schmidt, Anders, Martens, H. A., Hansen, H. H. & Thomsen, M. S., 23 Jun 2008, In: Neuroscience. 154, 2, p. 741-53 13 p.Research output: Contribution to journal › Journal article › Research
- Published
The nicotinic alpha7 acetylcholine receptor agonist ssr180711 is unable to activate limbic neurons in mice overexpressing human amyloid-beta1-42
Søderman, A., Thomsen, M. S., Hansen, H. H., Nielsen, E. Ø., Jensen, M. S., West, M. J. & Mikkelsen, Jens D., 28 Aug 2008, In: Brain Research. 1227, p. 240-7 8 p.Research output: Contribution to journal › Journal article › Research
- 2009
- Published
BDNF downregulates 5-HT(2A) receptor protein levels in hippocampal cultures
Trajkovska, V., Santini, M. A., Marcussen, A. B., Thomsen, M. S., Hansen, H. H., Mikkelsen, Jens D., Arneberg, L., Kokaia, M., Knudsen, G. M. & Aznar, S., 2009, In: Neurochemistry International. 55, 7, p. 697-702 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circadian and developmental regulation of N-methyl-d-aspartate-receptor 1 mRNA splice variants and N-methyl-d-aspartate-receptor 3 subunit expression within the rat suprachiasmatic nucleus
Bendová, Z., Sumová, A. & Mikkelsen, Jens D., 2009, In: Neuroscience. 159, 2, p. 599-609 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors: design, synthesis, and effects on behavior
Butini, S., Gemma, S., Campiani, G., Franceschini, S., Trotta, F., Borriello, M., Ceres, N., Ros, S., Coccone, S. S., Bernetti, M., De Angelis, M., Brindisi, M., Nacci, V., Fiorini, I., Novellino, E., Cagnotto, A., Mennini, T., Sandager-Nielsen, K., Andreasen, J. T., Scheel-Kruger, J. & 2 others, , 2009, In: Journal of Medicinal Chemistry. 52, 1, p. 151-69 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Melatonin controls seasonal breeding by a network of hypothalamic targets
Revel, F. G., Masson-Pévet, M., Pévet, P., Mikkelsen, Jens D. & Simonneaux, V., 2009, In: Neuroendocrinology. 90, 1, p. 1-14 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective cognitive deficits and reduced hippocampal brain-derived neurotrophic factor mRNA expression in small-conductance calcium-activated K+ channel deficient mice
Jacobsen, J. P. R., Redrobe, J. P., Hansen, H. H., Petersen, S., Bond, C. T., Adelman, J. P., Mikkelsen, Jens D. & Mirza, N. R., 2009, In: Neuroscience. 163, 1, p. 73-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
alpha(7) Nicotinic acetylcholine receptor activation prevents behavioral and molecular changes induced by repeated phencyclidine treatment
Thomsen, M. S., Christensen, D. Z., Hansen, H. H., Redrobe, J. P. & Mikkelsen, Jens D., 2009, In: Neuropharmacology. 56, 6-7, p. 1001-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Distinct neural pathways mediate alpha7 nicotinic acetylcholine receptor-dependent activation of the forebrain
Thomsen, M. S., Hay-Schmidt, Anders, Hansen, H. H. & Mikkelsen, Jens D., 2010, In: Cerebral Cortex. 20, 9, p. 2092-102 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct neural pathways mediate α7 nicotinic acetylcholine receptor-dependent activation of the forebrain
Thomsen, M. S., Hay-Schmidt, Anders, Hansen, H. H. & Mikkelsen, Jens D., 2010, In: Cerebral Cortex. 20, 9, p. 2092-102Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of brain-derived neurotrophic factor (BDNF) in the chronic unpredictable stress rat model and the effects of chronic antidepressant treatment
Larsen, M. H., Mikkelsen, Jens D., Hay-Schmidt, Anders & Sandi, C., 2010, In: Journal of Psychiatric Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plaque deposition dependent decrease in 5-HT2A serotonin receptor in AbetaPPswe/PS1dE9 amyloid overexpressing mice
Holm, P., Ettrup, A., Klein, A. B., Santini, M. A., El-Sayed, M., Elvang, A. B., Stensbøl, T. B., Mikkelsen, Jens D., Knudsen, Gitte Moos & Kleijn, S. A., 1 Jan 2010, In: Journal of Alzheimer's Disease. 20, 4, p. 1201-13 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Differential immediate and sustained memory enhancing effects of alpha7 nicotinic receptor agonists and allosteric modulators in rats
Thomsen, M. S., El-Sayed, M. & Mikkelsen, Jens D., 2011, In: PLOS ONE. 6, 11, p. e27014Research output: Contribution to journal › Journal article › Research
- Published
Hippocampal α7 nicotinic acetylcholine receptor levels in patients with schizophrenia, bipolar disorder, or major depressive disorder
Thomsen, M. S., Weyn, A. & Mikkelsen, Jens D., 2011, In: Bipolar Disorders (English Edition, Online). 13, 7-8, p. 701-7 7 p.Research output: Contribution to journal › Journal article › Research
- 2012
- Published
Epigenetic regulation of Arc and c-Fos in the hippocampus after acute electroconvulsive stimulation in the rat.
Dyrvig, M., Hansen, H. H., Christiansen, S. H. O., Woldbye, David Paul Drucker, Mikkelsen, Jens D. & Lichota, J., 2012, In: Brain Research Bulletin. 88, p. 507-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reprogrammering af modne celler til neuroner
Mikkelsen, Jens D., Rasmussen, M. A., Meyer, M. & Knudsen, G. M., 2012, In: Ugeskrift for Laeger. 174, 12, p. 786Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The α7 nicotinic acetylcholine receptor complex: one, two or multiple drug targets?
Thomsen, M. S. & Mikkelsen, Jens D., May 2012, In: Current Drug Targets. 13, 5, p. 707-20 14 p.Research output: Contribution to journal › Journal article › Research
- Published
Transient inactivation of the neonatal ventral hippocampus impairs attentional set-shifting behavior: reversal with an α7 nicotinic agonist
Brooks, J. M., Pershing, M. L., Thomsen, M. S., Mikkelsen, Jens D., Sarter, M. & Bruno, J. P., Oct 2012, In: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 37, 11, p. 2476-86 11 p.Research output: Contribution to journal › Journal article › Research
- Published
Type I and II positive allosteric modulators differentially modulate agonist-induced up-regulation of α7 nicotinic acetylcholine receptors
Thomsen, M. S. & Mikkelsen, Jens D., Oct 2012, In: Journal of Neurochemistry. 123, 1, p. 73-83 11 p.Research output: Contribution to journal › Journal article › Research
- Published
The α7 nicotinic acetylcholine receptor ligands methyllycaconitine, NS6740 and GTS-21 reduce lipopolysaccharide-induced TNF-α release from microglia
Thomsen, M. S. & Mikkelsen, Jens D., 15 Oct 2012, In: Journal of Neuroimmunology. 251, 1-2, p. 65-72 8 p.Research output: Contribution to journal › Journal article › Research
- 2013
- Published
Comparative analysis of kisspeptin-immunoreactivity reveals genuine differences in the hypothalamic Kiss1 systems between rats and mice
Overgaard, A., Tena-Sempere, M., Franceschini, I., Desroziers, E., Simonneaux, V. & Mikkelsen, Jens D., 2013, In: Peptides. 45, p. 85-90 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distribution and seasonal variation in hypothalamic RF-amide peptides in a semi-desert rodent, the jerboa
Janati, A., Talbi, R., Klosen, P., Mikkelsen, Jens D., Magoul, R., Simonneaux, V. & El Ouezzani, S., 2013, In: Journal of Neuroendocrinology. 25, 4, p. 402-411 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of a postnatal high-fat diet exposure on puberty onset, estrous cycle regularity, and kisspeptin expression in female rats
Lie, M. E. K., Overgaard, A. & Mikkelsen, Jens D., 2013, In: Reproductive Biology. 13, 4, p. 298-308 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gonadotropin-inhibitory hormone reduces sexual motivation but not lordosis behavior in female Syrian hamsters (Mesocricetus auratus)
Piekarski, D. J., Zhao, S., Jennings, K. J., Iwasa, T., Legan, S. J., Mikkelsen, Jens D., Tsutsui, K. & Kriegsfeld, L. J., 2013, In: Hormones and Behavior. 64, 3, p. 501-510 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Localized infusions of the partial alpha 7 nicotinic receptor agonist SSR180711 evoke rapid and transient increases in prefrontal glutamate release
Bortz, D. M., Mikkelsen, Jens D. & Bruno, J. P., 2013, In: Neuroscience. 255, p. 55-67Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabotropic glutamate receptor 2 and corticotrophin-releasing factor receptor-1 gene expression is differently regulated by BDNF in rat primary cortical neurons
Jørgensen, C. V., Klein, A. B., El-Sayed, M., Knudsen, G. M. & Mikkelsen, Jens D., 2013, In: Synapse. 67, 11, p. 794-800Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microduplication of 15q13.3 and Xq21.31 in a family with tourette syndrome and comorbidities
Melchior, L., Bertelsen, B., Debes, Nanette M Monique Mol, Groth, C., Skov, L., Mikkelsen, Jens D., Brøndum-Nielsen, K. & Tümer, Asuman Zeynep, 2013, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 162, 8, p. 825-831 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tesofensine induces appetite suppression and weight loss with reversal of low forebrain dopamine levels in the diet-induced obese rat
Hansen, H. H., Jensen, M. M., Overgaard, A., Weikop, Pia & Mikkelsen, Jens D., 2013, In: Pharmacology, Biochemistry and Behavior. 110, p. 265-271 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of perinatal exposure to ethinyl oestradiol or a mixture of endocrine disrupting pesticides on kisspeptin neurons in the rat hypothalamus
Overgaard, A., Holst, K., Mandrup, K., Boberg, J., Christiansen, S., Jacobsen, A. P., Hass, U. & Mikkelsen, Jens D., 2013, In: NeuroToxicology. 37, p. 154-162 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The mGlu2/3 Receptor Agonists LY354740 and LY379268 Differentially Regulate Restraint-Stress-Induced Expression of c-Fos in Rat Cerebral Cortex
Menezes, M. M., Santini, M., Benvega, M. J., Marek, G. J., Merchant, K. M., Mikkelsen, Jens D. & Svensson, K. A., 2013, In: Neuroscience Journal. 2013, 8 p., 736439.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhanced prefrontal serotonin 2A receptor signaling in the subchronic phencyclidine mouse model of schizophrenia
Santini, M. A., Ratner, C. F., Aznar, S., Klein, A. B., Knudsen, Gitte Moos, Mikkelsen, Jens D. & Klein, A. B., May 2013, In: Journal of Neuroscience Research. 91, 5, p. 634-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased serum brain-derived neurotrophic factor (BDNF) levels in patients with narcolepsy
Klein, A. B., Jennum, Poul, Knudsen, S., Gammeltoft, S. & Mikkelsen, Jens D., 7 Jun 2013, In: Neuroscience Letters. 544, p. 31-35 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced basal and novelty-induced levels of activity-regulated cytoskeleton associated protein (Arc) and c-Fos mRNA in the cerebral cortex and hippocampus of APPswe/PS1ΔE9 transgenic mice
Christensen, D. Z., Thomsen, M. S. & Mikkelsen, Jens D., Jul 2013, In: Neurochemistry International. 63, 1, p. 54-60 7 p.Research output: Contribution to journal › Journal article › Research
- Published
Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice
Jørgensen, C. V., Jacobsen, J. P., Caron, M. G., Klein, A. B., Knudsen, Gitte Moos & Mikkelsen, Jens D., 25 Oct 2013, In: Neuroscience Letters. 555, p. 118-22 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Disparate Changes in Kisspeptin and Neurokinin B Expression in the Arcuate Nucleus After Sex Steroid Manipulation Reveal Differential Regulation of the Two KNDy Peptides in Rats
Overgaard, A., Ruiz-Pino, F., Castellano, J. M., Tena-Sempere, M. & Mikkelsen, Jens D., 2014, In: Endocrinology. 155, 10, p. 3945-3955 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
D-serine deficiency attenuates the behavioral and cellular effects induced by the hallucinogenic 5-HT(2A) receptor agonist DOI
Santini, M. A., Balu, D. T., Puhl, M. D., Hill-Smith, T. E., Berg, A. R., Lucki, I., Mikkelsen, Jens D. & Coyle, J. T., 1 Feb 2014, In: Behavioural Brain Research. 259, p. 242-246 5 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
5-HT2A and mGlu2 receptor binding levels are related to differences in impulsive behavior in the Roman Low- (RLA) and High- (RHA) avoidance rat strains
Klein, A. B., Ultved, L., Adamsen, D., Santini, M. A., Tobeña, A., Fernandez-Teruel, A., Flores, P., Moreno, M., Cardona, D., Knudsen, Gitte Moos, Aznar, S. & Mikkelsen, Jens D., 28 Mar 2014, In: Neuroscience. 263, p. 36-45 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Photoperiodic Co-Regulation of Kisspeptin, Neurokinin B and Dynorphin in the Hypothalamus of a Seasonal Rodent
Bartzen-Sprauer, J., Klosen, P., Ciofi, P., Mikkelsen, Jens D. & Simonneaux, V., Aug 2014, In: Journal of Neuroendocrinology. 26, 8, p. 510-520 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transient inactivation of the ventral hippocampus in neonatal rats impairs the mesolimbic regulation of prefrontal glutamate release in adulthood
Bortz, D. M., Jørgensen, C. V., Mikkelsen, Jens D. & Bruno, J. P., Sep 2014, In: Neuropharmacology. 84, p. 19-30 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in RFamide-Related Peptide-1 (RFRP-1)-Immunoreactivity During Postnatal Development and the Estrous Cycle
Jørgensen, S. R., Andersen, M. D., Overgaard, A. & Mikkelsen, Jens D., Nov 2014, In: Endocrinology. 155, 11, p. 4402-4410 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of the Ly-6 family proteins Lynx1 and Ly6H in the rat brain is compartmentalized, cell-type specific, and developmentally regulated
Thomsen, M. S., Cinar, B., Jensen, M. M., Lyukmanova, E. N., Shulepko, M. A., Tsetlin, V., Klein, A. B. & Mikkelsen, Jens D., 17 Nov 2014, In: Brain Structure and Function (Print Edition). 219, 6, p. 1923-1934 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting Dopamine D3 and Serotonin 5-HT1A and 5-HT2A Receptors for Developing Effective Antipsychotics: Synthesis, Biological Characterization, and Behavioral Studies
Brindisi, M., Butini, S., Franceschini, S., Brogi, S., Trotta, F., Ros, S., Cagnotto, A., Salmona, M., Casagni, A., Andreassi, M., Saponara, S., Gorelli, B., Weikop, P., Mikkelsen, Jens D., Scheel-Kruger, J., Sandager-Nielsen, K., Novellino, E., Campiani, G. & Gemma, S., 26 Nov 2014, In: Journal of Medicinal Chemistry. 57, 22, p. 9578-9597 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of the CHRNA7 promoter variant −86T with Tourette syndrome and comorbid obsessive-compulsive disorder
Bertelsen, B., Melchior, L., Tümer, Asuman Zeynep, Groth, C., Mol Debes, N., Skov, L., Holst, K. K., Fagerlund, Birgitte & Mikkelsen, Jens D., 30 Nov 2014, In: Psychiatry Research. 219, 3, p. 710-711 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2015
Ovariectomy Drives Asynchronous Changes in Serotonin Receptor 2A and Transporter Availability in Rats
Frimer, N. A., Overgaard, A., Lie, M. E. K., Mikkelsen, Jens D. & Frokjaer, V. G., 2015, In: Journal of Steroids & Hormonal Science. 6, 3, p. 1-5 5 p., 1000161.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
α7 and β2 Nicotinic Acetylcholine Receptor Subunits Form Heteromeric Receptor Complexes that Are Expressed in the Human Cortex and Display Distinct Pharmacological Properties
Thomsen, M. S., Zwart, R., Ursu, D., Jensen, M. M., Pinborg, Lars Hageman, Gilmour, G., Wu, J., Sher, E. & Mikkelsen, Jens D., 2015, In: PLOS ONE. 10, 6, p. 1-16 16 p., e0130572.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels
Fisher, Patrick Mac Donald, Holst, K. K., Adamsen, D., Klein, A. B., Frøkjær, Vibe Gedsø, Jensen, P. S., Svarer, C., Gillings, N., Baare, W. F. C., Mikkelsen, Jens D. & Knudsen, G. M., Jan 2015, In: Human Brain Mapping. 36, 1, p. 313–323 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High plasma triglyceride levels strongly correlate with low kisspeptin in the arcuate nucleus of male rats
Overgaard, A., Axel, A. M., Lie, M. E., Hansen, H. H. & Mikkelsen, Jens D., Apr 2015, In: Endocrine Regulations. 49, 2, p. 51-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease
Jensen, M. M., Mikkelsen, Jens D., Arvaniti, M., Pinborg, Lars Hageman & Thomsen, M. S., 1 Apr 2015, In: Neurobiology of Aging. 36, 4, p. 1629-1638 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TSPO Imaging in Glioblastoma Multiforme: A Direct Comparison Between 123I-CLINDE SPECT, 18F-FET PET, and Gadolinium-Enhanced MR Imaging
Jensen, P., Feng, L., Law, Ian, Svarer, C., Knudsen, G. M., Mikkelsen, Jens D., de Nijs, R., Larsen, V. A., Dyssegaard, A., Thomsen, G., Fischer, W., Guilloteau, D. & Pinborg, Lars Hageman, Sep 2015, In: Journal of Nuclear Medicine. 56, 9, p. 1386-90 5 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Radiosynthesis and in vitro validation of (3)H-NS14492 as a novel high affinity alpha7 nicotinic receptor radioligand
Magnussen, J. H., Ettrup, A., Donat, C. K., Peters, D., Pedersen, M. H. F., Knudsen, G. M. & Mikkelsen, Jens D., 5 Sep 2015, In: European Journal of Pharmacology. 762, p. 35-41 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of Serotonin Transporter Changes in Depressive Responses to Sex-Steroid Hormone Manipulation: A Positron Emission Tomography Study
Frokjaer, V. G., Pinborg, Anja, Holst, K. K., Overgaard, A., Henningsson, S., Heede, M., Larsen, E. C., Jensen, P. S., Agn, M., Nielsen, A. P., Stenbæk, D. S., da Cunha-Bang, S., Lehel, S., Siebner, Hartwig Roman, Mikkelsen, Jens D., Svarer, C. & Knudsen, Gitte Moos, 15 Oct 2015, In: Biological Psychiatry. 78, 8, p. 534-43 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association Study of CHRNA7 Promoter Variants with Sensory and Sensorimotor Gating in Schizophrenia Patients and Healthy Controls: A Danish Case-Control Study
Bertelsen, B., Oranje, B., Melchior, L., Fagerlund, Birgitte, Werge, Thomas, Mikkelsen, Jens D., Tümer, Asuman Zeynep & Glenthøj, Birte Yding, Dec 2015, In: NeuroMolecular Medicine. 17, 4, p. 423-30 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1) Is a Selective Allosteric Antagonist of α7 Nicotinic Acetylcholine Receptor
Lyukmanova, E. N., Shulepko, M. A., Kudryavtsev, D., Bychkov, M. L., Kulbatskii, D. S., Kasheverov, I. E., Astapova, M. V., Feofanov, A. V., Thomsen, M. S., Mikkelsen, Jens D., Shenkarev, Z. O., Tsetlin, V. I., Dolgikh, D. A. & Kirpichnikov, M. P., 2016, In: PLOS ONE. 11, 2, p. 1-14 14 p., e0149733.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Encenicline, an α7 Nicotinic Acetylcholine Receptor Partial Agonist, Reduces Immune Cell Infiltration in the Colon and Improves Experimental Colitis in Mice
Salaga, M., Blomster, L. V., Piechota-Polańczyk, A., Zielińska, M., Jacenik, D., Cygankiewicz, A. I., Krajewska, W. M., Mikkelsen, Jens D. & Fichna, J., Jan 2016, In: Journal of Pharmacology and Experimental Therapeutics. 356, 1, p. 157-69 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regional brain volumes, diffusivity, and metabolite changes after electroconvulsive therapy for severe depression
Jorgensen, A., Magnusson, P., Hanson, L. G., Kirkegaard, T., Benveniste, H., Lee, H., Svarer, C., Mikkelsen, Jens D., Fink-Jensen, Anders, Knudsen, G. M., Paulson, Olaf B., Bolwig, T. G. & Jørgensen, Martin Balslev, Feb 2016, In: Acta Psychiatrica Scandinavica. 133, 2, p. 154-164 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in Binding of [123I]CLINDE, a High-Affinity Translocator Protein 18 kDa (TSPO) Selective Radioligand in a Rat Model of Traumatic Brain Injury
Donat, C. K., Gaber, K., Meixensberger, J., Brust, P., Pinborg, Lars Hageman, Hansen, H. H. & Mikkelsen, Jens D., Jun 2016, In: NeuroMolecular Medicine. 18, 2, p. 158-69 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex differences in the photoperiodic regulation of RF-Amide related peptide (RFRP) and its receptor GPR147 in the syrian hamster
Henningsen, J. B., Poirel, V., Mikkelsen, Jens D., Tsutsui, K., Simonneaux, V. & Gauer, F., 15 Jun 2016, In: Journal of Comparative Neurology. 524, 9, p. 1825-1838 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heteromeric α7β2 Nicotinic Acetylcholine Receptors in the Brain
Wu, J., Liu, Q., Tang, P., Mikkelsen, Jens D., Shen, J., Whiteaker, P. & Yakel, J. L., Jul 2016, In: Trends in Pharmacological Sciences. 37, 7, p. 562-74 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Functional interaction between Lypd6 and nicotinic acetylcholine receptors
Arvaniti, M., Jensen, M. M., Soni, N., Wang, H., Klein, A. B., Thiriet, N., Pinborg, Lars Hageman, Muldoon, P. P., Wienecke, Jacob, Imad Damaj, M., Kohlmeier, Kristi Anne, Gondré-Lewis, M. C., Mikkelsen, Jens D. & Thomsen, M. S., Sep 2016, In: Journal of Neurochemistry. 138, 6, p. 806-820 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of liraglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, in rat partial and full nigral 6-hydroxydopamine lesion models of Parkinson's disease
Hansen, H. H., Fabricius, K., Barkholt, P., Mikkelsen, Jens D., Jelsing, J., Pyke, C., Knudsen, L. B. & Vrang, N., 1 Sep 2016, In: Brain Research. 1646, p. 354-365 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lynx1 and Aβ1-42 bind competitively to multiple nicotinic acetylcholine receptor subtypes
Thomsen, M. S., Arvaniti, M., Jensen, M. M., Shulepko, M. A., Dolgikh, D. A., Pinborg, Lars Hageman, Härtig, W., Lyukmanova, E. N. & Mikkelsen, Jens D., Oct 2016, In: Neurobiology of Aging. 46, p. 13-21 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute phencyclidine administration induces c-Fos-immunoreactivity in interneurons in cortical and subcortical regions
Hervig, M. E., Thomsen, M. S., Kalló, I. & Mikkelsen, Jens D., 15 Oct 2016, In: Neuroscience. 334, p. 13-25 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Positive allosteric modulators of the α7 nicotinic acetylcholine receptor potentiate glutamate release in the prefrontal cortex of freely-moving rats
Bortz, D. M., Upton, B. A., Mikkelsen, Jens D. & Bruno, J. P., Dec 2016, In: Neuropharmacology. 111, p. 78-91Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of the functional expression of the Ca2+‐activated K+ channel KCa3.1 on microglia from adult human neocortical tissue
Blomster, L. V., Strøbaek, D., Hougaard, Charlotte Ørsted, Klein, J., Pinborg, Lars Hageman, Mikkelsen, Jens D. & Christophersen, P., Dec 2016, In: Glia. 64, 12, p. 2065-2078 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Roles of RFRP-3 in the daily and seasonal regulation of reproductive activity in female Syrian hamsters
Henningsen, J. B., Ancel, C., Mikkelsen, Jens D., Gauer, F. & Simonneaux, V., 2017, In: Endocrinology. 158, 3, p. 652-663Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The variability of translocator protein signal in brain and blood of genotyped healthy humans using in vivo 123I-CLINDE SPECT imaging: A test-retest study
Feng, L., Jensen, P., Thomsen, G., Dyssegaard, A., Svarer, C., Knudsen, L. V., Møller, Kirsten, Thomsen, C., Mikkelsen, Jens D., Guilloteau, D., Knudsen, Gitte Moos & Pinborg, Lars Hageman, 2017, In: Journal of Nuclear Medicine. 58, 6, p. 989-995 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The pan-Kv7 (KCNQ) Channel Opener Retigabine Inhibits Striatal Excitability by Direct Action on Striatal Neurons In Vivo
Hansen, H. H., Weikop, P., Mikkelsen, M. D., Rode, F. & Mikkelsen, Jens D., Jan 2017, In: Basic & Clinical Pharmacology & Toxicology Online. 120, 1, p. 46-51 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roles of RFRP-3 in the Daily and Seasonal Regulation of Reproductive Activity in Female Syrian Hamsters
Henningsen, J. B., Ancel, C., Mikkelsen, Jens D., Gauer, F. & Simonneaux, V., 1 Mar 2017, In: Endocrinology. 158, 3, p. 652-663 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perinatal nicotine treatment induces transient increases in NACHO protein levels in the rat frontal cortex
Wichern, F., Jensen, M. M., Christensen, D. Z., Mikkelsen, Jens D., Gondré-Lewis, M. C. & Thomsen, M. S., 27 Mar 2017, In: Neuroscience. 346, p. 278-283 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Preoptic Area and the RFamide-Related Peptide Neuronal System Gate Seasonal Changes in Chemosensory Processing
Jennings, K. J., Chasles, M., Cho, H., Mikkelsen, Jens D., Bentley, G., Keller, M. & Kriegsfeld, L. J., Nov 2017, In: Integrative and Comparative Biology. 57, 5, p. 1055-1065 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Analysis of gonadotrophin-releasing hormone-1 and kisspeptin neuronal systems in the nonphotoregulated seasonally breeding eastern rock elephant-shrew (Elephantulus myurus)
Medger, K., Bennett, N. C., Chimimba, C. T., Oosthuizen, M. K., Mikkelsen, Jens D. & Coen, C. W., 2018, In: The Journal of Comparative Neurology. 526, 15, p. 2388-2405Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons
Runegaard, A. H., Sørensen, Andreas Toft, Fitzpatrick, C. M., Jørgensen, Søren Heide, Petersen, A. V., Hansen, Nikolaj Winther, Weikop, Pia, Andreasen T., Jesper, Mikkelsen, Jens D., Perrier, Jean-Francois Marie, Woldbye, David Paul Drucker, Rickhag, Karl Mattias, Wörtwein, Gitta & Gether, Ulrik, 2018, In: eNeuro. 5, 3, 26 p., e0345.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Alpha7 nicotinic acetylcholine receptors and neural network synaptic transmission in human induced pluripotent stem cell-derived neurons
Larsen, H. M., Hansen, S. K., Mikkelsen, Jens D., Hyttel, P. & Stummann, T. C., 2019, In: Stem Cell Research. 41, 10 p., 101642.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA methylation regulates CHRNA7 transcription and can be modulated by valproate
Dyrvig, M., Mikkelsen, Jens D. & Lichota, J., Jun 2019, In: Neuroscience Letters. 704, p. 145-152Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis: [incl. Author Correction]
Pfisterer, U., Petukhov, V., Demharter, S., Meichsner, J., Thompson, J. J., Batiuk, M. Y., Martinez, A. A., Vasistha, Navneet A, Thakur, A., Mikkelsen, Jens D., Adorjan, I., Pinborg, Lars Hageman, Pers, Tune H, von Engelhardt, J., Kharchenko, P. V. & Khodosevich, K., 2020, In: Nature Communications. 11, 1, 19 p., 5038.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro and in vivo characterization of dibenzothiophene derivatives [125I]iodo-ASEM and [18F]ASEM as radiotracers of homo- And heteromeric α7 nicotinic acetylcholine receptors
Donat, C. K., Hansen, H. H., Hansen, H. D., Mease, R. C., Horti, A. G., Pomper, M. G., L’Estrade, E. T., Herth, Matthias Manfred, Peters, D., Knudsen, Gitte Moos & Mikkelsen, Jens D., 1 Jan 2020, In: Molecules. 25, 6, 19 p., 1425.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Low back pain scores correlate with the cytokine mRNA level in lumbar disc biopsies: a study of inflammatory markers in patients undergoing lumbar spinal fusion
Aripaka, S. S., jmn329, jmn329, Jørgensen, Louise Møller, Chughtai, S. A., Gaarde, C., Bendix, T. & Mikkelsen, Jens D., 2021, In: European Spine Journal. 30, p. 2967–2974 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
N1H- and N1-Substituted Phenylguanidines as alpha 7 Nicotinic Acetylcholine (nACh) Receptor Antagonists: Structure-Activity Relationship Studies
Alwassil, O., Khatri, S., Schulte, M. K., Aripaka, S. S., Mikkelsen, Jens D. & Dukat, M., 2021, In: ACS Chemical Neuroscience. 12, 12, p. 2194-2201 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synaptic Density and Neuronal Metabolic Function Measured by Positron Emission Tomography in the Unilateral 6-OHDA Rat Model of Parkinson’s Disease
Raval, N. R., Gudmundsen, F., Juhl, M., Andersen, Ida Vang, Speth, N., Videbæk, A., Petersen, I. N., Mikkelsen, Jens D., Fisher, P. M. D., Herth, Matthias Manfred, Plavén-Sigray, P., Knudsen, Gitte Moos & Palner, M., 2021, In: Frontiers in Synaptic Neuroscience. 13, 13 p., 715811.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Anti-Inflammatory Effect of Alpha7 Nicotinic Acetylcholine Receptor Modulators on BV2 Cells
trj450, trj450 & Mikkelsen, Jens D., 2022, In: Neuroimmunomodulation. 27, 4, p. 194-202 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression profile of synaptic vesicle glycoprotein 2A, B, and C paralogues in temporal neocortex tissue from patients with temporal lobe epilepsy (TLE)
Pazarlar, B. A., trj450, trj450, Petukhov, V., Pinborg, Lars Hageman, Khodosevich, Konstantin & Mikkelsen, Jens D., 2022, In: Molecular Brain. 15, 1, 45.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatio-Temporal Alterations in Synaptic Density During Epileptogenesis in the Rat Brain
Mikkelsen, Jens D., trj450, trj450, Bascuñana, P., Bankstahl, M., Bankstahl, J. P. & Pazarlar, B. A., 2022, In: Neuroscience. 499, p. 142-151 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 32177473
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Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease
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278
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Functional interaction between Lypd6 and nicotinic acetylcholine receptors
Research output: Contribution to journal › Journal article › Research › peer-review
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243
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Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons
Research output: Contribution to journal › Journal article › Research › peer-review
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