Claus Juul Løland
Professor
Neuropharm and Genetics
Blegdamsvej 3
2200 København N.
- 2010
- Published
Tandem Facial Amphiphiles for Membrane Protein Stabilization
Chae, P. S., Gotfryd, K., Pacyna, J., Miercke, L. J. W., Rasmussen, Søren Gøgsig Faarup, Robbins, R. A., Rana, R. R., Loland, Claus Juul, Kobilka, B., Stroud, R., Byrne, B., Gether, Ulrik & Gellman, S. H., 1 Dec 2010, In: Journal of the American Chemical Society. 132, 47, p. 16750-2 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
The binding sites for benztropines and dopamine in the dopamine transporter overlap
Jensen, H. B., Larsen, M. A. B., Mazier, S., Beuming, T., Weinstein, H., Shi, L., Loland, Claus Juul & Gether, Ulrik, 1 Jan 2011, In: Neuropharmacology. 60, 1, p. 182-90 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation
Kristensen, Anders Skov, Andersen, J., Jørgensen, T. N., Sørensen, L., Eriksen, J., Loland, Claus Juul, Strømgaard, Kristian & Gether, Ulrik, 1 Sep 2011, In: Pharmacological Reviews. 63, 3, p. 585-640 56 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Neuropeptide Y Y5 receptor antagonism attenuates cocaine-induced effects in mice.
Sørensen, G., Jensen, M., Weikop, Pia, Nielsen, D. D., Christiansen, S. H. O., Loland, Claus Juul, Bengtsen, C. H., Petersen, Jørgen Holm, Fink-Jensen, Anders, Wörtwein, Gitta & Woldbye, David Paul Drucker, Feb 2012, In: Psychopharmacology. 222, p. 565-577 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins
Chae, P. S., Rasmussen, Søren Gøgsig Faarup, Rana, R. R., Gotfryd, K., Kruse, A. C., Manglik, A., Cho, K. H., Nurva, S., Gether, Ulrik, Guan, L., Loland, Claus Juul, Byrne, B., Kobilka, B. K. & Gellman, S. H., 27 Jul 2012, In: Chemistry: A European Journal. 18, 31, p. 9485-90 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
R-modafinil (armodafinil): a unique dopamine uptake inhibitor and potential medication for psychostimulant abuse
Loland, Claus Juul, Mereu, M., Okunola, O. M., Cao, J., Prisinzano, T. E., Mazier, S., Kopajtic, T., Shi, L., Katz, J. L., Tanda, G. & Newman, A. H., Sep 2012, In: Biological Psychiatry. 72, 5, p. 405-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Steric hindrance mutagenesis in the conserved extracellular vestibule impedes allosteric binding of antidepressants to the serotonin transporter
Plenge, P., Shi, L., Beuming, T., Te, J., Newman, A. H., Weinstein, H., Gether, Ulrik & Loland, Claus Juul, 16 Nov 2012, In: The Journal of Biological Chemistry. 287, 47, p. 39316-26 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Use of dihydro-isobenzofuran in combination with serotonin reuptake inhibitors for CNS disease e.g. depression, anxiety, bipolar disorder, obsessive compulsory disorder
Bøgesø, K. P., Juhl, K., Zhong, H. & Loland, Claus Juul, 2013, IPC No. C07D-307/79, Patent No. WO2013110313-A1, Priority date 21 Aug 2013, Priority No. WOEP050952Research output: Patent
- Published
A rhodamine-labeled citalopram analogue as a high-affinity fluorescent probe for the serotonin transporter
Zhang, P., Jørgensen, T. N., Loland, Claus Juul & Newman, A. H., 1 Jan 2013, In: Bioorg. Med. Chem. Lett.. 23, 1, p. 323-326 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A virtual high-throughput screening approach to the discovery of novel inhibitors of the bacterial leucine transporter, LeuT
Simmons, K. J., Gotfryd, K., Billesbølle, C. B., Loland, Claus Juul, Gether, Ulrik, Fishwick, C. W. G. & Johnson, A. P., Mar 2013, In: Molecular Membrane Biology. 30, 2, p. 184-94 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study
Chae, P. S., Rana, R. R., Gotfryd, K., Rasmussen, Søren Gøgsig Faarup, Kruse, A. C., Cho, K. H., Capaldi, S., Carlsson, E., Kobilka, B., Loland, Claus Juul, Gether, Ulrik, Banerjee, S., Byrne, B., Lee, J. K. & Gellman, S. H., 21 Mar 2013, In: Chemical communications (Cambridge, England). 49, 23, p. 2287-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Correction to "tandem facial amphiphiles for membrane protein stabilization"
Chae, P. S., Gotfryd, K., Pacyna, J., Miercke, L. J. W., Rasmussen, Søren Gøgsig Faarup, Robbins, R. A., Rana, R. R., Loland, Claus Juul, Kobilka, B., Stroud, R., Byrne, B., Gether, Ulrik & Gellman, S. H., 28 Aug 2013, In: Journal of the American Chemical Society. 135, 34, p. 12922 1 p.Research output: Contribution to journal › Journal article › Research
- Published
Novel Tripod Amphiphiles for Membrane Protein Analysis
Chae, P. S., Kruse, A. C., Gotfryd, K., Rana, R. R., Cho, K. H., Rasmussen, Søren Gøgsig Faarup, Bae, H. E., Chandra, R., Gether, Ulrik, Guan, L., Kobilka, B. K., Loland, Claus Juul, Byrne, B. & Gellman, S. H., 2 Oct 2013, In: Chemistry: A European Journal. 19, 46Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design and synthesis of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile (citalopram) analogues as novel probes for the serotonin transporter S1 and S2 binding sites
Banala, A. K., Zhang, P., Plenge, P., Cyriac, G., Kopajtic, T., Katz, J. L., Loland, Claus Juul & Newman, A. H., 12 Dec 2013, In: Journal of Medicinal Chemistry. 56, 23, p. 9709-24 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
A Conserved Salt Bridge between Transmembrane Segment 1 and 10 Constitutes an Extracellular Gate in the Dopamine Transporter
Pedersen, A. V., Andreassen, T. F. & Loland, Claus Juul, 2014, In: Journal of Biological Chemistry. 289, 50, p. 35003-350014 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidation of Structural Elements for Selectivity across Monoamine Transporters: Novel 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues
Okunola-Bakara, O., Cao, J., Kopajtic, T., Katz, J. L., Loland, Claus Juul, Shi, L. & Newman, A. H., 2014, In: Journal of Medicinal Chemistry. 57, 3, p. 1000-1013 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Missense dopamine transporter mutations associate with adult parkinsonism and ADHD
Hansen, F. H., Skjørringe, T., Yasmeen, S., Arends, N. V., Sahai, M. A., Erreger, K., Andreassen, T. F., Holy, M., Hamilton, P. J., Neergheen, V., Karlsborg, M., Newman, A. H., Pope, S., Heales, S. J. R., Friberg, L., Law, I., Pinborg, L. H., Sitte, H. H., Loland, C., Shi, L. & 5 others, , 1 Jul 2014, In: The Journal of Clinical Investigation. 124, 7, p. 3107-20 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Deoxycholate-Based Glycosides (DCGs) for Membrane Protein Stabilisation
Bae, H. E., Gotfryd, K., Thomas, J., Hussain, H., Ehsan, M., Go, J., Loland, Claus Juul, Byrne, B. & Chae, P. S., 2015, In: ChemBioChem. 16, 10, p. 1454–1459 6 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Grafted biomembranes containing membrane proteins – the case of the leucine transporter
Jagalski, V., Barker, R. D., Thygesen, Mikkel Boas, Gotfryd, K., Krüger, M. B., Shi, L., Maric, S., Bovet, N. E., Moulin, M., Haertlein, M., Pomorski, Thomas Guenther, Loland, Claus Juul & Cardenas Gomez, M., 2015, In: Soft Matter. 11, 39, p. 7707-7711 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maltose neopentyl glycol-3 (MNG-3) analogues for membrane protein study
Cho, K. H., Husri, M., Amin, A., Gotfryd, K., Lee, H. J., Go, J., Kim, J. W., Loland, Claus Juul, Guan, L., Byrne, B. & Chae, P. S., 2015, In: The Analyst. 140, 9, p. 3157-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters
Stolzenberg, S., Quick, M., Zhao, C., Gotfryd, K., Khelashvili, G., Gether, Ulrik, Loland, Claus Juul, Javitch, J. A., Noskov, S., Weinstein, H. & Shi, L., 2015, In: The Journal of Biological Chemistry. 290, 22, p. 13992-4003 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel Xylene-Linked Maltoside Amphiphiles (XMAs) for Membrane Protein Stabilisation
Cho, K. H., Du, Y., Scull, N. J., Hariharan, P., Gotfryd, K., Loland, Claus Juul, Guan, L., Byrne, B., Kobilka, B. K. & Chae, P. S., 2015, In: Chemistry: A European Journal. 21, 28, p. 10008–10013 6 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
The use of LeuT as a model in elucidating binding sites for substrates and inhibitors in neurotransmitter transporters
Loland, Claus Juul, Mar 2015, In: BBA General Subjects. 1850, 3, p. 500-510 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Substrate-induced Unlocking of the Inner Gate Determines the Catalytic Efficiency of a Neurotransmitter: Sodium Symporter
Billesbolle, C. B., Kruger, M. B., Shi, L., Quick, M., Li, Z., Stolzenberg, S., Kniazeff, J., Gotfryd, K., Mortensen, Jonas Sigurd, Javitch, J. A., Weinstein, H., Loland, Claus Juul & Gether, Ulrik, 30 Oct 2015, In: Journal of Biological Chemistry. 290, 44, p. 26725-26738 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Structure-activity relationship studies of citalopram derivatives: examining substituents conferring selectivity for the allosteric site in the serotonin transporter
Larsen, M. A. B., Plenge, P., Andersen, J., Eildal, J. N. N., Kristensen, Anders Skov, Bøgesø, K. P., Gether, Ulrik, Strømgaard, Kristian, Bang-Andersen, B. & Loland, Claus Juul, Mar 2016, In: British Journal of Pharmacology. 173, 5, p. 925-936 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4359
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Grafted biomembranes containing membrane proteins – the case of the leucine transporter
Research output: Contribution to journal › Journal article › Research › peer-review
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Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR
Research output: Contribution to journal › Journal article › Research › peer-review
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195
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A Class of Rigid Linker-bearing Glucosides for Membrane Protein Structural Study
Research output: Contribution to journal › Journal article › Research › peer-review
Published