Andreas Toft Sørensen
Associate Professor
Neuropharm and Genetics
Blegdamsvej 3, 2200 København N.
Management and administration
Blegdamsvej 3
2200 København N.
- Published
A Novel Peripheral Action of PICK1 Inhibition in Inflammatory Pain
Jensen, Kathrine Louise, Noes-Holt, Gith, Sørensen, Andreas Toft & Madsen, Kenneth Lindegaard, 2021, In: Frontiers in Cellular Neuroscience. 15, 13 p., 750902.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain
Christensen, N. R., De Luca, M., Lever, M. B., Richner, M., Hansen, A. B., Noes-Holt, G., Jensen, K. L., Rathje, M., Jensen, D. B., Erlendsson, S., Bartling, C. R. O., Ammendrup-Johnsen, I., Pedersen, S. E., Schönauer, M., Nissen, K. B., Midtgaard, S. R., Teilum, K., Arleth, L., Sørensen, A. T., Bach, A. & 5 others, , 2020, In: EMBO Molecular Medicine. 12, 6, 25 p., e11248.Research output: Contribution to journal › Journal article › Research › peer-review
A robust activity marking system for exploring active neuronal ensembles
Sørensen, Andreas Toft, Cooper, Y. A., Baratta, M. V., Weng, F., Zhang, Y., Ramamoorthi, K., Fropf, R., LaVerriere, E., Xue, J., Young, A., Schneider, C., Gotzsche, C. R., Hemberg, M., Yin, J. C. P., Maier, S. F. & Lin, Y., 23 Sep 2016, In: eLife. 5, 9, 28 p., e13918.Research output: Contribution to journal › Journal article › Research › peer-review
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Activity-dependent long-term plasticity of afferent synapses on grafted stem/progenitor cell-derived neurons
Sørensen, Andreas Toft, Rogelius, N., Lundberg, C. & Kokaia, M., Jun 2011, In: Experimental Neurology. 229, 2, p. 274-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Activity-dependent volume transmission by transgene NPY attenuates glutamate release and LTP in the subiculum
Sørensen, Andreas Toft, Kanter-Schlifke, I., Lin, E. D., During, M. J. & Kokaia, M., Oct 2008, In: Molecular and Cellular Neuroscience. 39, 2, p. 229-37 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adeno-associated viral vector-induced overexpression of neuropeptide Y Y2 receptors in the hippocampus suppresses seizures
Woldbye, David Paul Drucker, Ängehagen, M., Gøtzsche, C. R., Elbrønd-Bek, H., Sørensen, Andreas Toft, Christiansen, S. H. O., Olesen, M. V., Nikitidou, L., Hansen, T. V. O., Kanter-Schlifke, I. & Kokaia, M., Sep 2010, In: Brain. 133, 9, p. 2778-88 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered Chloride Homeostasis Decreases the Action Potential Threshold and Increases Hyperexcitability in Hippocampal Neurons
Sørensen, Andreas Toft, Ledri, M., Melis, M., Nikitidou Ledri, L., Andersson, M. & Kokaia, M., 7 Dec 2017, In: eNeuro. 4, 6, e0172-17.2017 1–10.Research output: Contribution to journal › Journal article › Research › peer-review
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Behavioral encoding across timescales by region-specific dopamine dynamics
Jørgensen, Søren Heide, Ejdrup, Aske Lykke, Lycas, M. D., Posselt, Leonie Pauline, Madsen, Kenneth Lindegaard, Tian, L., Dreyer, J. K., Herborg, Freja, Sørensen, Andreas Toft & Gether, Ulrik, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 7, 10 p., e2215230120.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bidirectional protein–protein interactions control liquid–liquid phase separation of PSD-95 and its interaction partners
Christensen, N. R., Pedersen, Christian Parsbæk, Sereikaité, Vita, Pedersen, J. N., Vistrup-Parry, M., Sørensen, Andreas Toft, Otzen, D., Teilum, Kaare, Madsen, Kenneth Lindegaard & Strømgaard, Kristian, 2022, In: iScience. 25, 2, 26 p., 103808.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chemogenetic Modulation of G Protein-Coupled Receptor Signalling in Visual Attention Research
Jørgensen, Søren Heide, Fitzpatrick, C. M., Gether, Ulrik, Woldbye, David Paul Drucker & Sørensen, Andreas Toft, Nov 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 5, p. 373-381 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Combined gene overexpression of neuropeptide Y and its receptor Y5 in the hippocampus suppresses seizures.
Gøtzsche, C. R., Nikitidou, L., Sørensen, Andreas Toft, Olesen, M. V., Sørensen, G., Christiansen, S. H. O., Ängehagen, M., Woldbye, David Paul Drucker & Kokaia, M., 2012, In: Neurobiology of Disease. 45, p. 288-96 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Detection of endogenous NPY release determined by novel GRAB sensor in cultured cortical neurons
Christensen, Emma Kragelund, Konomi Pilkati, Ainoa, Rombach, Joscha, Comaposada Baro, Raquel, Wang, H., Li, Y. & Sørensen, Andreas Toft, 2023, In: Frontiers in Cellular Neuroscience. 17, 12 p., 1221147.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential Effect of Neuropeptides on Excitatory Synaptic Transmission in Human Epileptic Hippocampus
Ledri, M., Sørensen, Andreas Toft, Madsen, M. G., Christiansen, S. H., Ledri, L. N., Cifra, A., Bengzon, J., Lindberg, E., Pinborg, L. H., Jespersen, B., Gotzsche, C. R., Woldbye, David Paul Drucker, Andersson, M. & Kokaia, M., 1 Jul 2015, In: Journal of Neuroscience. 35, 26, p. 9622-9631 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of chemogenetic inhibition on dopamine and norepinephrine neurons in the mouse 5-choice serial reaction time task
Fitzpatrick, C. M., Runegaard, A. H., Christiansen, S. H., Hansen, Nikolaj Winther, Jørgensen, Søren Heide, McGirr, J. C., de Diego Ajenjo, A., Sørensen, Andreas Toft, Perrier, Jean-Francois Marie, Petersen, A., Gether, Ulrik, Woldbye, David Paul Drucker & Andreasen T., Jesper, 2019, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 90, 2, p. 264-276 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors
Woldbye, David Paul Drucker, Nanobashvili, A., Sørensen, Andreas Toft, Husum, H., Bolwig, T. G., Sørensen, G., Ernfors, P., Kokaia, M. & Sørensen, G., 1 Dec 2005, In: Neurobiology of Disease. 20, 3, p. 760-72 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Editorial: Gene Therapy in the CNS – Progress and Prospects for Novel Therapies
Ledri, M., Sørensen, Andreas Toft, Kokaia, M., Woldbye, David Paul Drucker & Gøtzsche, C. R., 2021, In: Frontiers in Molecular Neuroscience. 14, 778134.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Encyclopedia of Basic Epilepsy Research: Epilepsy and Gene Therapy: Resculpturing synaptic transmission with neuropeptides
Kokaia, M. & Sørensen, Andreas Toft, 27 May 2009, Encyclopedia of Basic Epilepsy Research: Epilepsy and Gene Therapy: Resculpturing synaptic transmission with neuropeptides. Schwartzkroin, PA. (ed.). Elsevier Ltd. Academic Press, Vol. 3. p. 1430-34 5 p.Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research › peer-review
- Published
Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model
Tønnesen, J., Parish, C. L., Sørensen, Andreas Toft, Andersson, A., Lundberg, C., Deisseroth, K., Arenas, E., Lindvall, O. & Kokaia, M., 4 Mar 2011, In: PLOS ONE. 6, 3, p. e17560Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional properties and synaptic integration of genetically labelled dopaminergic neurons in intrastriatal grafts
Sørensen, Andreas Toft, Thompson, L., Kirik, D., Björklund, A., Lindvall, O. & Kokaia, M., May 2005, In: European Journal of Neuroscience. 21, 10, p. 2793-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functionally Distinct Neuronal Ensembles within the Memory Engram
Sun, X., Bernstein, M. J., Meng, M., Rao, S., Sørensen, Andreas Toft, Yao, L., Zhang, X., Anikeeva, P. O. & Lin, Y., 2020, In: Cell. 181, 2, p. 410-423 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Galanin gene transfer curtails generalized seizures in kindled rats without altering hippocampal synaptic plasticity
Kanter-Schlifke, I., Sørensen, Andreas Toft, Ledri, M., Kuteeva, E., Hökfelt, T. & Kokaia, M., 19 Dec 2007, In: Neuroscience. 150, 4, p. 984-92 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hippocampal NPY gene transfer attenuates seizures without affecting epilepsy-induced impairment of LTP
Sørensen, Andreas Toft, Nikitidou, L., Ledri, M., Lin, E. D., During, M. J., Kanter-Schlifke, I. & Kokaia, M., Feb 2009, In: Experimental Neurology. 215, 2, p. 328-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease
Herborg, F., Jensen, K. L., Tolstoy, S., Arends, N., Posselt, L. P., Shekar, A., Aguilar, J., Lund, V. K., Erreger, K., Rickhag, M., Lycas, M. D., Lonsdale, M. N., Rahbek-Clemmensen, T., Sorensen, A. T., Newman, A. H., Lokkegaard, A., Kjaerulff, O., Werge, T., Moller, L. B., Matthies, H. J. G. & 4 others, , 2021, In: JCI insight. 6, 18, 21 p., 151496.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of a Descending Prefrontal Circuit Prevents Ketamine-Induced Stress Resilience in Females
Dolzani, S. D., Baratta, M. V., Moss, J. M., Leslie, N. L., Tilden, S. G., Sørensen, Andreas Toft, Watkins, L. R., Lin, Y. & Maier, S. F., 26 Feb 2018, In: eNeuro. 5, 1, p. 1-18 18 p., e0025-18.2018.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Jasper’s Basic mechanisms of the Epilepsies: Gene Therapy of Focal-Onset Epilepsy Using Adeno-Associated Virus Vector-Mediated Overexpression of Neuropeptide Y
Noe, F., Sørensen, Andreas Toft, Kokaia, M. & Vezzani, A., 2013, Jasper's Basic Mechanisms of the Epilepsies: Gene Therapy of Focal-Onset Epilepsy Using Adeno-Associated Virus Vector-Mediated Overexpression of Neuropeptide Y. Noebels, J. L., Avoli, M., Rogawski, M. A., Olsen, R. W. & Delgado-Escueta, A. V. (eds.). 4 ed. Oxford University Press, p. 1139-1149 11 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
ID: 144763187
Most downloads
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287
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A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
243
downloads
Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
155
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Altered Chloride Homeostasis Decreases the Action Potential Threshold and Increases Hyperexcitability in Hippocampal Neurons
Research output: Contribution to journal › Journal article › Research › peer-review
Published