Professor and Director of the Human Migraine Research Unit, the Danish Headache Center and Department of Neurology, Rigshospitalet Glostrup
Title: Targeting downstream intracellular signaling in migraine
Abstract: Migraine is a complex disease characterized by recurrent episodes of headache accompanied by nausea, vomiting, and/or sensitivity to light and sound. The two most prevalent types of migraine are migraine either with or without aura. A key feature of migraine is that various endogenous or exogenous triggers can initiate an attack. This quality provides us with the unique opportunity to explore disease mechanisms by experimentally inducing attacks in humans. Recent data suggest that intracellular molecules and channels play an integral mechanistic role in migraine pathophysiology.