Karl Mattias Rickhag
Neuropharm and Genetics
Blegdamsvej 3, 2200 KÃ¸benhavn N.
Name: Mattias Rickhag
Adress: Grisslevägen 3
City: 227 32 Lund
Phone: + 46-46-2111931
Cell Phone: + 46734-434948
Birth date: 13th of March, 1978
Education and employment
2015- Assistant Professor in Neuropharmacology at Molecular Neuropharmacology Laboratory, Dept. of Neuroscience and Pharmacology, Univ. of Copenhagen,
2010-2015 Post-doctoral fellow (individual 3-year grant from the Lundbeck Foundation), Molecular Neuropharmacology Laboratory, University of Copenhagen, Denmark
2008-2010 Post-doctoral fellow (individual 3-year grant from the Danish Research Council, FSS), Molecular Neuropharmacology Laboratory, University of Copenhagen, Denmark
2007 Post-doctoral fellow at Laboratory for Experimental Brain Research,Lund University, Sweden
2007 PhD in Neuroscience at Lund University (24th February). Thesis title:”Gene Expression Changes and Brain Plasticity after Experimental Stroke”. Supervisor: Prof. Tadeusz Wieloch
2003-2007 PhD-student in neuroscience at Laboratory for Experimental Brain Research, Lund University, Sweden
1998-2002 Masters in Biomedical Science, four-year undergraduate program, Lund University, Sweden
1997-1998 Military service in the Swedish Air Force
1993-1997 Senior High School in biological sciences, Vetlanda, Sweden
Research supervision and management
i) Co-supervision of three master students and two bachelor students at Molecular Neuropharmacology Laboratory, University of Copenhagen. Supervision involved both theoretical as well as experimental guidance within neuropharmacology, histology and in vivo models.
ii) Co-supervisor for PhD student Annika Thomsen (enrolled in April 2014) at Molecular Neuropharmacology Laboratory, University of Copenhagen headed by Prof. Gether.
iii) Daily supervision of laboratory technicians for more than six years.
iv) Submission of all animal license applications to the Danish Animal Inspectorate Agency and Danish Working Environment Authority at Molecular Neuropharmacology Laboratory, University of Copenhagen.
v)Management and responsibility for genetically modified mouse lines (approximately ten different mouse lines) at Molecular Neuropharmacology Laboratory, University of Copenhagen.
- In vivo
Mouse genetics, transcardial perfusion, drug administration (subcutaneous, intraperitoneal, intravenous), SHIRPA screen, assessment of locomotion and psychostimulant-induced hyperlocomotion, sensitization, sensori-motor function tests (rotating pole test, cylinder test), and animal breeding
- Virus mediated expression techniques in vivo
Expression of genetically reengineered receptors (G protein coupled receptors or ligand-gated ion channels) activated by synthetic ligands
Immunohistochemistry/-cytochemistry, fresh/frozen tissue section preparations using cryostat and vibratome, acute brain slice preparations, staining techniques, in situ hybridization
- Molecular biology
In situ hybridization, PCR, RNA extraction, quantitative real-time PCR, genotyping, microarrays
Competitive binding assays to assess binding affinity and binding sites, saturation binding and uptake assays, autoradiography
SDS-PAGE/immunoblotting,immunoprecipitation, co-immunoprecipitation, surface biotinylation, synaptosomal preparations,andcell trafficking assays
- Additional experience
Fluorescence activated cell sorting (FACS) of dopaminergic neurons, confocal/light microscopy, lentiviral transduction
Attendee/presenter of scientific data during the following conferences:
Dopamine 2013, Alghero, Italy (2013)
43th Annual Meeting for Society of Neuroscience, San Diego, USA (2013)
Membrane Transport Proteins, Les Diablerets, Switzerland, July (2012)
41th Annual Meeting for Society of Neuroscience, Washington DC, USA (2011)
40th Annual Meeting for Society of Neuroscience, San Diego, USA (2010)
Membrane Transport Proteins, Biddeford, USA (2010)
39th Annual Meeting for Society of Neuroscience, Chicago, USA (2009)
38th Annual Meeting for Society of Neuroscience, Washington DC, USA (2008)
35th Annual Meeting for Society of Neuroscience, Washington DC, USA (2005)
34th Annual Meeting for Society of Neuroscience, San Diego, USA (2004)
Invited speaker at the following conference:
Molecular Imaging in Medical Research, Greifswald, Germany (2012)
World Pharma 2010:Bridging Basic and Clinical Pharmacology, Copenhagen, Denmark (2010)
3rd Scandinavian conference on Molecular Physiology of Channels and Transporters, Sigtuna, Sweden, (2010)
Visiting scientist at the following research group:
Department of Pharmacology, Faculty of Medicine, Université de Montréal, Montréal, Québec, Canada. Invitation by Professor Louis-Eric Trudeau (in April 2014)
AGY Therapeutics Inc., San Francisco, USA (for two weeks during 2003)
Proficiency in written and spoken English. Some experience in German and French.
Microsoft Office (Word, Excel, PowerPoint), Adobe Illustrator, Adobe Photoshop,
Adobe Acrobat Reader, ImageJ and GraphPad (for statistical analysis).
Co-inventor for the rights to ”Sigma ligands for neuronal regeneration and functional recovery (Filed patent to US Patent and Trademark Office) January 27th, 2005.