We invite highly motivated, dedicated and skilled students to contact us for an interview. We have long-term experience with supervision of bachelor and Master’s students with different backgrounds (human biology, medicine, molecular biomedicine, biology, biochemistry). Competent and committed supervision has our highest priority and projects are designed to full-fill the criteria of the individual study.
We value scientific excellence, creativity, knowledge sharing, helpfulness and dedication in our laboratories. We offer a dynamic and international research environment involving a large network of collaborators around the world.
Bachelor and Master’s projects are available in the following areas:
In vivo studies of cellular interactions and blood flow in health and disease
In the Lauritzen lab we work on a range of projects all related to the brain physiology and blood vasculature. Our focus is how the brain is kept healthy with aging and in disease. We have many years of experience in in vivo physiology in mice using basic electrophysiological and laser-optic techniques, transgenic mice, and 2-photon microscopy. If you have some time to invest you can get experience with microsurgery and live imaging of brain cells and vessels through cranial windows.
Neurotransmitter release: mechanisms, regulation and disease
Are you interested in knowing how neurotransmitters are released by vesicular exocytosis within one millisecond of the arrival of an action potential? Are you interested in using patch-clamp and advanced fluorescence techniques to study neurotransmitter release in real time? Do you want to know how this machine is working – and how it is regulated, for instance during learning? Do you want to know how mutation or other insults to the release machinery lead to diseases such as epilepsy, schizophrenia or intellectual disability? Do you want to come up with ideas how to counteract such mutations/insults, and find new ways to treat disease?
If one or more of these questions sound interesting to you please contact Jakob B. Sørensen
Cellular regulation and molecular genetics of neurotransmitter transporters and receptors
Are you interested in molecular and cellular neurobiology? Do you want to understand how neurons control activity and availability of neurotransmitter receptors and transporters in the synapse? Are you interested in understanding how mutations in these proteins contribute to CNS-diseases such as depression, ADHD, Parkinson’s disease, schizophrenia and addiction? Do you want to know how you become addicted to drugs such as cocaine or amphetamine?
If one or more of these questions sound interesting to you please contact Ulrik Gether
Molecular pharmacology and structure of neurotransmitter transporters
Would you like to know how membrane proteins like neurotransmitter transporters work at the molecular level? Are you interested in using crystallography and advanced fluorescence techniques to study their transport function? Do you want to characterize how drugs act on neurotransmitter transporters? Are you interested in finding new ways to discover drugs for treatment of e.g. cocaine addiction and depression?
Neuronal scaffolding proteins and protein trafficking
Are you interested in how neuronal scaffolding proteins regulate synaptic signaling processes? Would you like to know if scaffolding proteins could be a new target for treatment of CNS-diseases such as stroke and addiction? Would you like to understand the role of membrane-shaping protein domains (e.g. BAR domains) in neuronal scaffolding? Do you want to know how BAR domain proteins control protein trafficking not only in neurons but also in other cells such as endocrine cells?
Impact of cannabis on motor control
Several patients suffering from neurodegenerative diseases self-medicate with cannabis to get rid of symptoms such as tremor and spasms. Our aim is to understand how cannabis affects the neural networks responsible for motor control. We are looking for a motivated student to be part of an exciting research project involving pharmacology, behavioural tests and electrophysiology.