The effect of metrizamide on regional brain glucose metabolism in the rat.

Research output: Contribution to journalJournal articleResearchpeer-review

The X-ray contrast material metrizamide is structurally related to 2-deoxyglucose and inhibits brain glucose phosphorylation in vitro. In vivo, the present autoradiographic study with labeled 2-deoxyglucose revealed a global reduction of brain glucose phosphorylation after metrizamide administration in the cisterna magna of rats. The reduction averaged 18% of all regions.
Original languageEnglish
JournalActa Neurologica Scandinavica
Issue number4
Pages (from-to)249-53
Number of pages4
Publication statusPublished - 1984
Externally publishedYes

ID: 14944221