Glucose metabolism in small subcortical structures in Parkinson's disease

Research output: Contribution to journalJournal articleResearchpeer-review

  • Per Borghammer
  • Søren B Hansen
  • Carsten Eggers
  • Mallar Chakravarty
  • Kim Vang
  • Joel Aanerud
  • Rüdiger Hilker
  • Wolf-Dieter Heiss
  • Anders Rodell
  • Ole Lajord Munk
  • David Keator
  • Gjedde, Albert
Evidence from experimental animal models of Parkinson's disease (PD) suggests a characteristic pattern of metabolic perturbation in discrete, very small basal ganglia structures. These structures are generally too small to allow valid investigation by conventional positron emission tomography (PET) cameras. However, the high-resolution research tomograph (HRRT) PET system has a resolution of 2 mm, sufficient for the investigation of important structures such as the pallidum and thalamic subnuclei.
Original languageEnglish
JournalActa Neurologica Scandinavica
Issue number5
Pages (from-to)303-10
Number of pages8
Publication statusPublished - May 2012

    Research areas

  • Aged, Brain, Brain Diseases, Metabolic, Case-Control Studies, Female, Glucose, Humans, Male, Middle Aged, Parkinson Disease, Positron-Emission Tomography

ID: 44913803